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-
- Type:
- Document
- Date Created:
- 1981
- Collection:
- System Dynamic Society Records
- Collecting Area:
- University Archives
- Collection ID:
- ua435
- Parent Record(s):
- 23d738ba88f8333bc39725f9cb5bd0b8, 4a97153f59047c298f3bcd6b15c284f5, and e8eac154b3129692f26c222dbc2c9466
- Description:
- In order to investigate the regulation of breathing under various conditions, we have developed a dynamic model of the human respiratory and cardio-vascular systems. The model describes the flows of oxygen and carbon dioxide between the atmosphere and the tissues as well as the chemical regulation of breathing in a rather detailed manner. When testing the model with a step increase in muscular metabolism (simulating a transition from rest to physical activity), it reproduces clinical observations for the variation in ventilation and in arterial oxygen and carbon dioxide pressures. The model also reproduces the respiratory response to changes in the composition of the inspired air. Combined with a model of the Hafnia A anaesthetic system, the respiratory system model has finally been used to examine the life-threatening dynamical run-away effects which may occur, if the fresh gas flow is reduced too much, and the patient starts to rebreathe his own expiration.