In order to investigate the regulation of breathing under various conditions, we have developed a dynamic model of the human respiratory and cardio-vascular systems. The model describes the flows of oxygen and carbon dioxide between the atmosphere and the tissues as well as the chemical regulation of breathing in a rather detailed manner. When testing the model with a step increase in muscular metabolism (simulating a transition from rest to physical activity), it reproduces clinical observations for the variation in ventilation and in arterial oxygen and carbon dioxide pressures. The model also reproduces the respiratory response to changes in the composition of the inspired air. Combined with a model of the Hafnia A anaesthetic system, the respiratory system model has finally been used to examine the life-threatening dynamical run-away effects which may occur, if the fresh gas flow is reduced too much, and the patient starts to rebreathe his own expiration.

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Date created

• 1981

Type

• Document

Processing Activity

• Processing documentation available at: https://wiki.albany.edu/display/SCA/Processing+Ingested+Digital+Files

License

• Creative Commons BY-NC-ND Attribution-NonCommercial-NoDerivs 4.0 International

  
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ITEM CONTEXT

Part of

e8eac154b3129692f26c222dbc2c9466

Scope and Contents

Part of

4a97153f59047c298f3bcd6b15c284f5

Scope and Contents

Part of

23d738ba88f8333bc39725f9cb5bd0b8

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Collection

System Dynamic Society Records

Scope and Contents

Collecting area

• This collection is part of the University Archives