Biology Instrumentation Interdisciplinary Studies, B.S., 2014

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Office of the Provost & Vica President for Academic Affalrs

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UNIVERSITY
ATALBANY

State University of New York

May 15, 2014

Elizabeth L. Bringsjord

Interim Provost and Vice Chancellor
State University of New York
System Administration

State University Plaza

Albany, NY 12246

Dear Dr, Bringsjord,

On behalf of the faculty at the University at Albany, I am pleased to submit a proposal to revise
our BS in Interdisciplinary Studies. By way of this proposal we seek to add a concentration in
Bio-instrumentation.

This revision has been fully considered and approved through our campus governance system.
Should there be a need for additional information or clarification to facilitate processing, please
contact Suzanne Freed, Assistant Vice Provost for Undergraduate Education at

streed@albany.edu.

Thank you for your consideration and assistance.

Sincerely,

Pear bff

Susan D. Phillips, Ph.D,
Provost and Vice President for Academic Affairs

Enclosure

c. Dr. Jeanette Altarriba, Vice Provost and Dean for Undergraduate Education
Dr. Phil Nasca, Dean, School of Public Health
Dr. Mary Gallant, Associate Dean for Academic Affairs, School of Public Health
Ms, Suzanne Freed, Asst Vice Provost for Undergraduate Education

University Hall, 308
1400 Washington Avenue, Albany, New York: 12222
pH: $18-956-8030 Fx: 518-956-043
ywewalbanyeda

he Sate iv 3
erteow ver Program Revision Proposal:

Changes to an Existing P oer

SUNY approval and SED registration are required for many changes to registered programs. To request a change to a
registered program leading to an undergraduate degree, a graduate degree, or a certificate that does not involve the creation
of a new program, 1 a Chief Executive or Chief Academic Officer must submit a signed cover letter and this completed
form to the SUNY Provost at program.review@suny.edu,

. Institution Name: University at Albany, State University of New York

. Institution’s 6-digit SED Institution Code: 210500

. Institution’s Address: 1400 Washington Ave Albany, NY 12222

. Additional Information: Specify each campus and its 6-digit SED Institution Code where the
program is registered and where the proposed changes would apply.

Bwye

1. Program title: Interdisciplinary Studies with a concentration in Bio-Instrumentation

2. Award (e.g. B.A., M.S,):; Bachelor of Science (BS)

3. Number of Required Credits: Minimum [ 120 ] If tracks or options, largest minimum [ —_]

4, HEGIS Code: 4901

5, SED Inventory of Registered Programs (IRP) 5-digit Program Code: 04653

6. Anticipated effective date of the change in the program(s) (mm/dd/yyyy): August 25,2014

7. If the current program(s) must remain registered until enrolled students have graduated, the
anticipated effective date by which continuing students will have completed the current version
of the program(s): N/A

Name and title: Suzanne K Freed

Asst Vice Provost for Undergraduate Education
Telephone: 518-242-6046
E-mail: sfreed@albany.edu

Signature affirms that the proposal has met all applicable campus administrative and
shared governance procedares for consultation, and the institution’s commitment to support
the program as revised.

Name and title: Susan D. Phillips, Phi.
Pr and Vic ‘ident-for Academic Affairs
Signature and date: SHSLU" ey

Partner institution’s nam
Name and title of partner institution’s CEO:

Signature of partner institution’s CEO (or append a signed letter indicating approval of this
proposal):

Version 2013-10-21

4 To propose changes that would create a new program, the Program Revision Proposal form for Creating New
Program(s) from Existing Program(s) is required.
2 If the partner institution is non-degree-granting, see CEO Memo 94-04,

1

| Section 2. Requested Changes.

[Section 2.1. Changes in Program Content

a) Check all that apply. Describe each proposed change and why it is proposed.

[ ] Cumulative change from SED’s last approval of the registered program of one-third or more of the minimum credits
required for the award (e.g., 20 credits for associate degree programs, 40 credits for bachelor’s degree programs)

[ ] Changes ina program's focus or design

[x ]Adding or eliminating one or more options, concentrations or tracks

[ ] Adding or eliminating a requirement for program completion (such as an intemship, clinical placement, cooperative
education, or other work or field-based experience)

[ ] Altering the liberal arts and science content in a way that changes the degree classification of an undergraduate
program, as defined in Section 3.47(c)(1-4) of Regents Rules

Biological research has been revolutionized in the last 15-20 years, in large part by advances in hio-
instrumentation. These advances have provided the capacity to increase the scope and throughput of research
activities. This expansion in scope has resulted in the development of new fields of study. For example,
molecular biologists have long been interested in understanding the structure and function of genes and
proteins, but due to technological limitations were restricted to studying one or at most a few genes or
proteins during the course of their careers. Advances in instrumentation for techniques such as DNA
sequencing, quantitative PCR, microarray analysis, 2D gel electrophoresis, and mass spectrometry now allow
scientists to simultaneously study all of the genes and proteins of an organism, and have resulted in the new
fields of genomics and proteomics. The continued evolution and refinement of this instrumentation now
Places the ability to perform such studies within the reach of most research laboratories, and thus individuals
Pursuing exrphoyimentin tectuscal research will likely be utilizing instrumentation of this type during their

The University at Albany has made significant investments in bio-instrumentation through the creation of first
the Center for Functional Genomics and then the Cancer Research Center (CRC). Core laboratories within the
CRC are equipped with state-of-the-art instumentation for molecular biology, genomics, proteomics, and cell
analysis research. The laboratories include instrumentation for DNA sequencing, Next Generation sequencing,
quantitative PCR, nucleic acid extraction, microarray analysis, 2D electrophoresis, mass spectrometry, flow
cytometry, and laser capture microdissection. With this proposal to establish an Interdisciplinary Studies
major with a concentration in bio-instrumentation, we can extend our use of these resources for the

education of undergraduate students.

b) Provide a side-by-side comparison of all the courses in the existing and proposed revised program that clearly indicates
all new or significantly revised courses, and other changes.

Bio-instrumentation is a new concentration.
Introductory Science and Math courses (38 credits)

ABIO120 General Biology I (3 credits)
ABIO121 General Biology II (3 credits)
ABIO 201 General Biology I Lab (1 credit)

2
ABIO 202Z General Biology II Lab (1 credit)

ABIO 212Y Introductory Genetics (4 credits)
ABIO 217 Cell Biology (3 credits)
ACHM120 General Chemistry I (3 credits)
ACHM 124 General Chemistry I Lab (1 credit)

ACHM121 General Chemistry II (3 credits)
ACHM125_ General Chemistry II Lab (1 credit)

A CHM 220 Organic Chemistry I (3 credits)
ACHM 222 Organic Chemistry I Lab (1 credit)
AMAT 108 Elementary Statistics (3credits)
AMAT 112. Calculus! (4 credits)
A PHY 140 Physics I: Mechanics (3 credits)
A PHY 145 Physics LabI (1 credit)

Public Health C ore Requirements (12 credits)

HSPH 201
HSPH 231
HSPH 332

HBMS 505

Introduction to Public Health (3credits)
Concepts in Epidemiology (3 credits)
Introduction to Biostatistics:

Collection, Analysis & Interpretation

of Public Health Data (3 credits)

Biological Basis of Public Health (3 credits)

Bio-Instrumentation Requirements (25 credits)

Bio-Instrumentation Core Courses (16 credits)

HBMS 310

HBMS 311

HMBS 312

HBMS 314

Molecular and Genomic Approaches

in Biotechnolgy I (4 credits)
Molecular and Genomic Approaches

in Biotechnology II (4 credits)
Poteomic Methodologies

in Biotechnology (4 credits)
Animal and Cell Culture

Model Systems (4 credits)

Instrurentation in Biotechnology Research Internship Courses (6 credits)

(Two from the following) Each (3 credits)

HBMS 410
HBMS 411
HMBS 412
HMBS 414
HBMS 415

Instrumentation in Biotechnology Research Intemship, Molecular Core Lab
Instrumentation in Biotechnology Research Intemship, Proteomics Core Lab
Instrumentation in Biotechnology Research Intemship, Genomics Core Lab
Instrumentation in Biotechnology Research Intemship, Cell Analysis Lab
Instrumentation in Biotechnology Research Intemship, Academic Lab

Bio- Instrumentation Cooperative Training Internship (3 credits)

HBMS 420

Bio-Instrumentation Cooperative Training Intemship
3
a) Foreachneworsignificantly revised course, provide a syllabus at the end of this form, and, on the SUNY Faaulty
Tahle provide the name, qualifications, and relevant experience of the faculty teaching each new or significantly revised
course. NOTE: Syllabi for all courses should be available upon request. Each syllabus should show that all work for
credit is college level and of the appropriate rigor. Syllabi generally include a course description, prerequisites and.
corequisites, the number of lecture and/or other contact hours per week, credits allocated (consistent with SUNY
policy on credit/contact hours), general course requirements, and expected student learning outcomes.

See Appendix 1
c) What are the additional costs of the change, if any? If there are no anticipated costs, explain why.

The University at Albany has made significant investments in bio-instrumentation through the creation of
first the Center for Functional Genomics and then the Cancer Research Center (CRC). Core laboratories
within the CRC are equipped with state-of-the-art instrumentation for molecular biology, genomics,
proteomics, and cell analysis research. The laboratories include instrumentation for DNA sequencing, Next
Generation sequencing, quantitative PCR, nucleic acid extraction, microarray analysis, 2D electrophoresis,
mass spectrometry, flow cytometry, and laser capture microdissection. With this proposal to establish an
undergraduate degree program in bio-instrumentation, we seek to maximize the University’ s investment in
this research instrumentation by using these resources for the education of undergraduate students. Existing
personnel resources within the School of Public Health and the Cancer Research Center are sufficient to
meet the needs required by our current student projections, for administration, advising and instruction.

[Section 2.2. Other Changes

Check all that apply. Describe each proposed change and why it is proposed.

Mode of delivery
NOTES: (1) If the change in delivery enables students to complete 50% of more of the program via distance
education, submit a Distance Education Format Proposal as part of this proposal. (2) If the change involves
adding an accelerated version of the program that impacts financial aid eligibility or licensure qualification, SED
may register the version as a separate program

[ ] Fonet change(s) (e.g., from full-time to part-time), based on SED definitions, for the entire program
1) State proposed format(s) and consider the consequences for financial aid
2) Describe availability of courses and any change in faculty, resources, or support services.

[ ] A change in the total number of credits in a certificate or advanced certificate program

[ ] Any change to a registered licensure-qualifying program, or the addition of licensure qualification to an existing
program. Exception: Small changes in the required number of credits in a licensure-qualifying program that do not
involve a course or courses that satisfy one of the required content areas in the profession.

[Section 3. Sample Program Schedule

a) Forundergraduate programs, complete the SUNY Undergraduate Sample Program Schedule to show the sequencing
and scheduling of courses in the program. If the program has separate tracks or concentrations, complete a Sample
Program Schedule for each one.
NOTE: The Undergraduate Schedule must show all curricular requirements and demonstrate that the program

conforms to SUNY’s and SED’s policies.

e It must show howa student can complete all program requirements within SUNY credit limits, unless a longer
period is selected as a format in Item 2.1(c): two years of full-time study (or the equivalent) and 64 credits for an
associate degree, or four years of full-time study (or the equivalent) and 126 credits for a bachelor’s degree.
Bachelor’ s degree programs should have at least 45 credits of upper division study, with 24 in the major.

e — Tt must show howstudents in A.A., A.S. and bachelor’s programs can complete, within the first two years of full-
time study (or 60 credits), no fewer than 30 credits in approved SUNY GER courses, with at least 3 credits each
in Basic Communication and Mathematics, plus no fewer than three credits each in at least 5 of the following 8
categories: Natural Science, Social Science, American History, Western Civilization, Other World Civilizations,
Humanities, the Arts and Foreign Languages.

Tt must show how students can complete Liberal Arts and Sciences (LAS) credits appropriate for the degree.
When a SUNY Transfer Path applies to the program, it must show how students can complete an appropriate
number of SUNY Transfer Path (TPath) courses (fromthe Transfer Path Requirement Summary) within the first
two years of full-time study (or 60 credits), consistent with SUNY’s Student Seamless Transfer policy.

e Requests for a programlevel waiver of SUNY credit limits, SUNY GER and/or a SUNY Transfer Path require the
campus to submit a Waiver Request - a different form- with compelling justification(s).

See Appendix 2; could not format to fit page.

[Section 4. SUNY Faculty Table ]

a) If applicable, provide information on faculty members who will be teaching new or significantly revised courses in the
program. Expand the table as needed.

b) Append at the end of this document position descriptions or announcements for each to-be-hired faculty member

(a) b) © (@) @) 0)
% of
Time Program Discipline(s) of Additional
Faculty Member Name and | Dedicat Courses Highest and Other Highest and Qualifications: List
Title and/or Rank at the ed to Which May | Applicable Earned Other related certifications
Institution This Be Taught Degrees (include Applicable and licenses and
(Include and identify Progra | (Number and College or Earned Degrees | professional experience
Program Director.) m Title) University) in field.

Program Director: 60% BMS 310 - PhD., Albany Microbiology and | Part-time Instructor,
John Tine Molecular and | Medical College, Immunology Microbiology, Hudson

Genomic 1989 Valley Community
Director, Molecular Genetics Approaches in Biology College (2009-present)
Laboratory, Biotechnology | B.S., Siena College,
UAlbany Cancer Research. I 1982
Conte: BMS 410-
Adjunct Assistant Professor, pomenaion
Sepa of Biological Biotechnology

ences

UAlbany Reseach

Intemship,

Molecular Core

Lab

(a) b) © (d) (e) a)
% of
Time Program Discipline(s) of Additional
Faculty Member Name and | Dedicat Courses Highest and Other Highest and Qualifications: List
Title and/or Rank at the ed to Which May | Applicable Earned Other related certifications
Institution This Be Taught Degrees (include Applicable and licenses and
(Include and identify Progra | (Number and College or Earned Degrees | professional experience
Program Director.) m Title) University) in field.
Stidar Chittur 40% BMS 311 - PhD., School of Medicinal Adjunct Assistant
Molecularand | Pharmacy, West Chemistry Professor, Center for
Director, High-Throughput Genomic Virginia University, Cell Biology & Cancer
Genomics Laboratory, Approachesin | 1996 Research, Albany
UAlbany Cancer research. Biotechnology Medical College (2010-
Center Il B.Pharm, The Pharmacy present)
BMS 412- Bombay College of
Research Associate Professor, I ion i PostDoc, Purdue
Department of Biomedical at uments University of University, School of
Sciences, UAlbany SPH Biotechnology Bombay, 1991 ao Sciences
Research
Intemship,
Genomics Core
Lab
Qishan Lin 40% BMS 312 - PhD., Institute of Analytical PostDoc, University of
Proteomic Chemistry, Chinese | Chemistry Washington, Howard
Director, Proteomics Facility, Methodologies | Academy of Hughes Medical Institute
UAlbany Cancer Research. in Sciences, 1996 (2000)
Center Biotechnology
BMS411- MSc., Institute of Organic PostDoc, Albany
Research Associate Professor, I 7 Photographic Chemistry Medical College (2002)
Department of Biomedical in Chemistry, Chinese
Sciences, UAlbany SPH i A
Biotechnology of Sciences, 1991
ntemship | B.Sc, Nalional Chemistry
mics naa
Core La University of
Defense &
Technology, China,
1988
Brian Parr 40% BMS 314- PhD., Comell History of Director, University of
Animal and University, 1986 Evolutionary Colorado Cancer Center,
Director, Transgenic Mouse/ Cell Culture Biology Transgenic/ Knockout
Cell Culture/Laser Capture Model Systems | M.S., University of Core Facility (2004-
Microdissection Facilities, BMS414- Virginia, 1980 Physiology 2007)
UAlbany Cancer Research. I 7
Center in B.A., Haverford Assistant Professor,
e College, 1977 University of Colorado,
Research Associate Professor, Biotechnology Boulder (1995-2003)
Department of Biomedical I ip, Call
Sciences, UAlbany SPH Analysis Core
Lab

(a) b) © (d) (e) a)
% of
Time Program Discipline(s) of Additional
Faculty Member Name and | Dedicat Courses Highest and Other Highest and Qualifications: List
Title and/or Rank at the ed to Which May | Applicable Earned Other related certifications
Institution This Be Taught Degrees (include Applicable and licenses and
(Include and identify Progra | (Number and College or Earned Degrees | professional experience
Program Director.) m Title) University) in field.
Martin Tenniswood. 20% BMS 415 - PhD., Queen’s Biochemistry Director, Center for
Instrumentation | University, Canada, Functional Genomics
Director, Cancer Research in 1979 (2009-present)
Center Professor, Department Biotechnology Chemistry
of Biomedical Sciences Research B.Sc., Trent Director, Molecular
Intemship, University, Canada, Biology Core Facility,
Academic Lab | 1973 Adirondack Biomedical
SNS 450 - Reserch Institute (1994
A )
Bio-
Instrumentation
Cooperative
Training
Intemship
BMS 505 -
Biological
Basis of Public
Health
JoEllen Welsh 15% BMS 415 - PhD., Comell Nutitional PostDoc, University of
Instrumentation | University, 1980 Biochemistry Ottawa, Canada, (1983-
Professor, Department of in 1985)
Environmental Health Sciences Biotechnology | B.A., Rutgers
Research University, 1975 Biology Director, How
Intemship, Cytometry and Sorting
Academic Lab Facility, University of
BMS 420 - Notre Dame
Bio-
Instrumentation
Cooperative
Training
Intemship
Douglas Conklin 15% BMS 415 - PhD., University of | Molecular Co-Inventor, siRNAs
Instrumentation | Wisconsin-Madison, | Biology
Associate Professor, in 1992 PostDoc, Cold Spring
Department of Biomedical Biotechnology Harbor Laboratory,
Sciences Research B.S., University of Microbiology (1993-1997)
Intemship, Pittsburgh, 1985
Academic Lab
BMS 420-
Bio-
Instrumentation
Cooperative
Training
Intemship

(a) b) © (d) (e) a)
% of
Time Program Discipline(s) of Additional
Faculty Member Name and | Dedicat Courses Highest and Other Highest and Qualifications: List
Title and/or Rank at the ed to Which May | Applicable Earned Other related certifications
Institution This Be Taught Degrees (include Applicable and licenses and
(Include and identify Progra | (Number and College or Earned Degrees | professional experience
Program Director.) m Title) University) in field.
Jason Herschkowitz 15% BMS 415 - PhD., University of | Genetics & PostDoc, Baylor College
Instrumentation | North Carolina, Molecular of Medicine, (2008-
Assistant Profe in 2008 Biology 2013)
Department of Biomedical Biotechnology
Sciences Research MES., George Forensic Science
Intemship, Washington
Academic Lab | University, 2000
Medical
BMS 20- | BS, SUNY Technology
Instrumentation Buffalo, 1998
Cooperative
Training
Intemship
Ramune Reliene 15% BMS 415 - PhD., Swiss Federal | Biochemistry PostDoc, University of
Instumentation | Institute of Califomia Los Angeles,
Assistant Professor, in Technology, 2001 (2001-2005)
Department of Environmental Biotechnology
Health Sciences Research MS,, University of | Biochemistry PostDoc, Lymphoma
Intemship, Vilnius, 1996 Research Foundation
Academic Lab (2005-2007)
B.S., University of Biochemi:
BMS420- | Vilnius 1904 aid
Bio-
Instumentation
Cooperative
Training
Intemship
Dwight Williams 20% SPH 201 - MS.W., Rutgers Social Work Director, Northeast
Inho to Public | University, 1971 Regional Public Health
Clinical Professor, Department Health Leadership Institute
of Health Policy, Management, (NEPHLI), NYS
& Behavior Department of Health
(1996-2012)
Director, Undergraduate Public
Health Program, School of Chief Health Planner,
Public Health Bureau of Health Facility
Planning, NYS
Department of Health
(1985-1996)
Health Executive
Development.
Comell
University (1985)
Elizabeth Vasquez 10% SPH/EPI 231- | Dr-P.H., NewYork | Epidemiology Research Scientist,
Concepts in Medical College, Helen Hayes Hospital,
Assistant Professor, Epidemiology | 2010 ‘West Haverstraw, NY
Department of Epidemiology Epidemiology (2002-2010)
and Biostatistics MP.H., Columbia
University, 2002

(a) b) © (d) (e) a)
% of
Time Program Discipline(s) of Additional
Faculty Member Name and | Dedicat Courses Highest and Other Highest and Qualifications: List
Title and/or Rank at the ed to Which May | Applicable Earned Other related certifications
Institution This Be Taught Degrees (include Applicable and licenses and
(Include and identify Progra | (Number and College or Earned Degrees | professional experience
Program Director.) m Title) University) in field.
Igor Kuznetsov 10% SPH/EPI 332- | Ph.D., Mount Sinai | Biomathematics PostDoc, Mount Sinai
Introduction to | School of Medicine, School of Medicine,
Associate Professor, Biostatistics New York New Y ork University,
Gen*NY*sis Center for University, 2003 (2008)
Excellence in Cancer Genomics Biomathematics
and Department of M-Phil., Mount Research Associate,
Epidemiology and Biostatistics Sinai School of Dept of Molecular
Medicine, New Biosciences, University
York University, Cell Biology and | of Kansas (2003-2004)
2001 Genetics
MS. equiv.,
Novosibirsk State

Anju Menon

5%

SPH/EPI 332 -
Introduction to
Biostatistics

MS,, University of
Louisiana at
Lafayette, 2010

MS,, University of
Connecticut, 2008

Part 2. Part-Time Faculty

Mathematics

Statistics

PhD student in
Biostatistics (2010 -
present)

Statistical Programmer,
NYS Department of
Health (2011)

Part 3. To-Be-Hired Faculty
(List as TBH1, TBH2, etc.,
and provide expected hiring
date instead of name.)

University at Albany
Program Revision — Interdisciplinary Studies

Appendix 1

Syllabi for new classes
Molecular and Genomic Approaches in Biotechnology |
BMS 310, Fall 2014
Syllabus

Location and Meeting Times:
Lecture: Tu/Th 10:30am — 11:50am, TBD (tentative Massry Conference Center)
Laboratory: We 9:00am — 12:00pm, CRC 211

Course Director:

John Tine, Ph.D.

School of Public Health

University at Albany, SUNY

Cancer Research Center, 1 Discovery Drive
Tel: 518-591-7212

Office: CRC 342C, hours TBD
jtine@albany.edu

Teaching Assistant: TBD
Course Description:

This course is the first of a two course sequence. The goal of this course is to provide students
with a solid theoretical background in molecular biological and advanced genomic technologies,
hands on experience in the performance of many of these techniques and an understanding of
the instrumentation required to perform them, and an appreciation for how these technological
tools can be applied to address research questions in the life sciences. The course will begin
with an overview of basic molecular biology techniques such as purification, enzymatic
manipulation, and separation of nucleic acids, PCR, and hybridization. The course will then
focus on more advanced technologies such as DNA sequencing and quantitative PCR and the
instrumentation required to perform these technologies. Applications of the technologies will
be highlighted, including sequencing, gene expression analysis, genotyping, epigenetic studies,
etc.

The lecture topics will be partnered with laboratory exercises that provide hands-on experience
so that students develop a more full understanding of these technologies. A focus will be on the
instrumentation required to perform the various technologies. While instrument operation and
data analysis will be highlighted, there will be significant coverage of other key issues such as
instrument design, maintenance, quality control calibrations, and troubleshooting.

Prerequisites:

A BIO 212Y Introductory Genetics, or equivalent from another institution
A BIO 217 Cell Biology, or equivalent from another institution
Course Learning Objectives:

1. Students will demonstrate an understanding of basic molecular biology techniques in both
theory and performance.

2. Students will develop and demonstrate a thorough understanding of DNA sequencing, the
instrumentation required for its performance, and the analysis of DNA sequence data.

3. Students will demonstrate an ability to generate DNA sequence by performing reactions and
operating the instrumentation necessary to obtain this data.

4. Students will demonstrate analyze and troubleshoot the quality of DNA sequence by use of
software tools for data analysis.

5. Students will develop and demonstrate a thorough understanding of quantitative PCR, the
instrumentation required for its performance, the analysis of qPCR data, and the
applications that are facilitated by this technology.

6. Students will demonstrate an ability to generate qPCR data by performing reactions and
operating the instrumentation necessary to obtain this data.

7. Students will demonstrate an ability to analyze qPCR data by use of software tools for data
analysis.

8. Students will demonstrate an understanding and utilization of appropriate laboratory safety
procedures.

Reading Materials:

There is no assigned textbook for the course. Reading materials will be assigned by the course
instructor and posted on the course Blackboard site as appropriate. These readings will be
derived from the current scientific literature, and may change to reflect technological advances.
All readings will be available for student access prior to the appropriate lecture or laboratory
session.

Grading:

Lecture: Three tests will be administered to assess students comprehension of material
covered in lecture. The tests can contain a mixture of both objective (multiple
choice, true-false) and short essay questions. The lecture grade will be an average
of the test grades

Laboratory: To assess performance in the laboratory component of the course, 2-3 lab reports
will be assigned. The laboratory grade will be an average of the lab report grades.

Final grade: The lecture grade will comprise 75%, and the laboratory grade 25%, of the final
course grade.
The grading scale for the course is follows:

A= 93-100 A-= 90-92

B+ = 87-89 B = 83-88 B- = 80-82
C+ = 77-79 C= 73-78 C-= 70-72
D+ = 67-69 D = 63-68 D- = 60-62
E=0-59

Class Policies:

Attendance:

Safety:

Electronics:

Regular attendance is necessary for academic achievement in this course. The
instructor should be notified promptly in case of absence, with a valid reason
provided. For absences related to medical issues, please refer to the University’s
Medical Excuse Policy (www.albany.edu/health_center/medicalexcuse.shtml). If
absent from lecture, the student is responsible for all material covered during that
session. If absent from laboratory, the student will be provided with an alternative
exercise that will need to be completed. More than three unexcused absences in
lecture or laboratory will result in a 5% reduction of the lecture or laboratory
component of the final course grade.

Students are required to adhere to the University’s laboratory safety guidelines
during laboratory sessions. These guidelines will be reviewed during the first
laboratory session.

As a courtesy to your fellow students and faculty, the active use of cell phones
(including text messaging) is not allowed during class time.

Academic Integrity:

Students are expected to adhere to university policies on academic integrity (see
http://www.albany.edu/undergraduate_bulletin/regulations.html). Any form of
academic dishonesty, including cheating or plagiarism, will not be tolerated and
will lead to disciplinary action as deemed appropriate by the faculty and/or the
University's judicial process.

From the University’s Standards of Academic Integrity Policy, Fall 2013:
“Every student has the responsibility to become familiar with the standards of academic integrity

at the Univers.
integrity, and

‘ity. Faculty members must specify in their syllabi information about academic
may refer students to this policy for more information. Nonetheless, student claims

of ignorance, unintentional error, or personal or academic pressures cannot be excuses for
violation of academic integrity. Students are responsible for familiarizing themselves with the
standards and behaving accordingly, and UAlbany faculty are responsible for teaching, modeling
and upholding them. Anything less undermines the worth and value of our intellectual work, and
the reputation and credibility of the University at Albany degree.”
Course Schedule:

Lecture: The material to be covered during the course lectures is arranged into topics. The
coverage of topics will be spread over multiple lecture sessions (80 minutes each,
approximately 26 sessions total). The lecture topics to be covered during the
course are shown in the table below.

Laboratory: The laboratory component of this course is designed to complement the schedule
of lecture topics. There will be one laboratory session per week (3 hours each,
approximately 13 sessions total). Activities for some topics will be spread over
multiple laboratory sessions. The laboratory topics to be covered during the
course are shown in the table below.

Lecture/Laboratory Schedule:

Week Day Topic
Week 1 Tue Course introduction, Nucleic acid purification
Thurs Enzymatic manipulation of nucleic acids |
Lab (Wed) Laboratory safety
Week 2 Tue Enzymatic manipulation of nucleic acids II
Thurs Polymerase chain reaction |
Lab (Wed) Nucleic acid purification, Enzymes |
Week 3 Tue Polymerase chain reaction II, Nucleic acid hybridization
Thurs DNA sequencing - overview
Lab (Wed) Enzymes Il, PCR
Week 4 Tue Test 1
Thurs DNA sequencing - chemistries
Lab (Wed) PCR-RFLP analysis
Week 5 Tue DNA sequencing — design considerations
Thurs DNA sequencing — separation/detection
Lab (Wed) DNA sequencing |: instrumentation overview
Week 6 Tue DNA sequencing instruments
Thurs DNA sequencing — data analysis/troubleshooting
Lab (Wed) DNA sequencing II: reactions
Week 7 Tue DNA sequence analysis software |
Thurs DNA sequence analysis software II
Lab (Wed) DNA sequencing III: run, maintenance considerations
Week 8 Tue DNA sequencing strategies
Thurs Quantitative PCR — overview of technology
Lab (Wed) DNA sequencing IV: data analysis/ troubleshooting/apps
Week 9 Tue Test 2
Thurs qPCR — assay design

Lab (Wed)

qPCR I: instrumentation overview

Week 10 Tue qPCR — experimental considerations and design
Thurs qPCR — instrumentation
Lab (Wed) QPCR II: assay/experimental design
Week 11 Tue qPCR — data analysis, software
Thurs qPCR — applications |
Lab (Wed) QPCR Ill: templates/reactions
Week 12 Tue qPCR — applications II
Thurs qPCR — applications III
Lab (Wed) QPCR IV: instrument set-up/run/maintenance considerations
Week 13 Tue Automation in qPCR
Thurs qPCR quality control
Lab (Wed) qPCR V: applications
Week 14 Tue Review
Thurs Test 3
Lab (Wed) Open

Molecular and Genomic Approaches in Biotechnology II
BMS 311, Spring 2015

Location and meeting times:
Lecture: T/Th 1:00pm -2:20 pm, TBD (tentative Massry Conference Center)
Laboratory: W 1:00pm — 4:00pm, CRC 211

Course Director:

Sridar V. Chittur PhD

Department of Biomedical Sciences

Director, Microarray & HT Sequencing Core
Center for Functional Genomics, SUNY Albany
One Discovery Dr, CRC342G, hours TBD
Rensselaer, NY 12144

Tel:518-591-7215

schittur@albany.edu
Teaching Assistant: TBD
Course Description

This course is the second of a two course sequence. The goal of this course is to provide
students with a solid theoretical background in advanced genomic technologies, hands on
experience in the performance of many of these techniques and an understanding of the
instrumentation required to perform them, and an appreciation for how these technological
tools can be applied to address research questions in the life sciences. The main focus of the
course will be on advanced genomic technologies such as digital PCR, microarray analysis, Next
Generation Sequencing and the instrumentation required to apply these technologies.
Applications of the technologies will be highlighted, including gene expression and copy number
analysis, genotyping, epigenetic studies, study of DNA binding proteins, etc.

The lecture topics will be partnered with laboratory exercises that provide hands-on experience
so that students develop a more full understanding of these technologies. A focus will be on the
instrumentation required to perform the various technologies. While instrument operation and
data analysis will be highlighted, there will be significant coverage of other key issues such as
instrument design, maintenance, quality control calibrations, and troubleshooting.

Prerequisites

BMS 310, Molecular and Genomic Approaches in Biotechnology |

Student Objectives

1. Students will develop and demonstrate a thorough understanding of digital PCR, the

instrumentation required for its performance, the analysis of digital PCR data, and the
applications that are facilitated by this technology.
2. Students will develop and demonstrate a thorough understanding of microarray analysis,
the instrumentation required for its performance, the analysis of microarray data, and the
applications that are facilitated by this technology.

3. Students will demonstrate an ability to generate and analyze microarray data by performing
target preparation, operating instrumentation, and performing data analysis.

4. Students will be able to describe the application of various microarrays in clinical settings.

5. Students will develop and demonstrate a thorough understanding of Next Generation
Sequencing approaches and the applications that are facilitated by these approaches.

6. Students will be able to utilize high throughput genomic data and perform pathway analysis.

7. Students will learn about emerging nucleic acid technologies and how they can be applied to
diagnostics.

8. Students will demonstrate an understanding and utilization of appropriate laboratory safety
procedures.

Reading Materials:

There is no assigned textbook for the course. Reading materials will be assigned by the course
instructor and posted on the course Blackboard site as appropriate. These readings will be
derived from the current scientific literature, and may change to reflect technological advances.
All readings will be available for student access prior to the appropriate lecture or laboratory
session.

Grading

Lecture: Three tests will be administered to assess students comprehension of material
covered in lecture. The tests can contain a mixture of both objective (multiple
choice, true-false) and short essay questions. The lecture grade will be an average
of the test grades

Laboratory: To assess performance in the laboratory component of the course, 2-3 lab reports
will be assigned. The laboratory grade will be an average of the lab report grades.

Final grade: The lecture grade will comprise 75%, and the laboratory grade 25%, of the final
course grade.

The grading scale for the course is follows:

A= 93-100 A- = 90-92
B+ = 87-89 B = 83-88
C+ = 77-79 C=73-78
D+ = 67-69 D = 63-68 D- = 60-62
E=0-59

Class Policies:
Attendance: Regular attendance is necessary for academic achievement in this course. The
instructor should be notified promptly in case of absence, with a valid reason
provided. For absences related to medical issues, please refer to the University’s
Medical Excuse Policy (www.albany.edu/health_center/medicalexcuse.shtml). If
absent from lecture, the student is responsible for all material covered during that
session. If absent from laboratory, the student will be provided with an alternative
exercise that will need to be completed. More than three unexcused absences in
lecture or laboratory will result in a 5% reduction of the lecture or laboratory
component of the final course grade.

Safety: Students are required to adhere to the University’s laboratory safety guidelines
during laboratory sessions. These guidelines will be reviewed during the first
laboratory session.

Electronics: Asa courtesy to your fellow students and faculty, the active use of cell phones
(including text messaging) is not allowed during class time.

Academic Integrity:

Students are expected to adhere to university policies on academic integrity (see
http://www.albany.edu/undergraduate_bulletin/regulations.html). Any form of
academic dishonesty, including cheating or plagiarism, will not be tolerated and
will lead to disciplinary action as deemed appropriate by the faculty and/or the
University's judicial process.

From the University’s Standards of Academic Integrity Policy, Fall 2013:

“Every student has the responsibility to become familiar with the standards of academic integrity
at the University. Faculty members must specify in their syllabi information about academic
integrity, and may refer students to this policy for more information. Nonetheless, student claims
of ignorance, unintentional error, or personal or academic pressures cannot be excuses for
violation of academic integrity. Students are responsible for familiarizing themselves with the
standards and behaving accordingly, and UAlbany faculty are responsible for teaching, modeling
and upholding them. Anything less undermines the worth and value of our intellectual work, and
the reputation and credibility of the University at Albany degree.”

Course Schedule:

Lecture: The material to be covered during the course lectures is arranged into topics. The
coverage of topics will be spread over multiple lecture sessions (80 minutes each,
approximately 26 sessions total). The lecture topics to be covered during the
course are shown in the table below.

Laboratory: The laboratory component of this course is designed to complement the schedule
of lecture topics. There will be one laboratory session per week (3 hours each,
approximately 13 sessions total). Activities for some topics will be spread over
multiple laboratory sessions. The laboratory topics to be covered during the
course are shown in the table below.

Lecture/Laboratory Schedule:

Week Day Topic
Week 1 Tue Course introduction, Digital PCR overview
Thurs Digital PCR — assay and experimental design
Lab (Wed) Laboratory safety
Week 2 Tue Digital PCR — instrumentation
Thurs Digital PCR — applications
Lab (Wed) Digital PCR, instrumentation, run
Week 3 Tue Microarray — overview
Thurs Microarray approaches |
Lab (Wed) Digital PCR data analysis
Week 4 Tue Microarray approaches II
Thurs Test
Lab (Wed) Microarray template preparation
Week 5 Tue Microarray experimental design
Thurs Microarray methods |
Lab (Wed) Microarray hybridization
Week 6 Tue Microarray methods II
Thurs Instrumentation for microarray analysis |
Lab (Wed) Microarray scan
Week 7 Tue Instrumentation for microarray analysis II
Thurs Microarray data extraction and analysis
Lab (Wed) Microarray data extraction, analysis
Week 8 Tue Microarray downstream data analysis |
Thurs Microarray downstream data analysis II
Lab (Wed) Microarray downstream analysis |
Week 9 Tue Microarray applications |
Thurs Microarray applications II
Lab (Wed) Microarray downstream analysis II
Week 10 Tue Microarray applications III
Thurs Microarray quality control
Lab (Wed) Next Gen sequencing: instrumentation overview
Week 11 Tue Test 2
Thurs Next Generation sequencing technology
Lab (Wed) Next Gen sequencing: template preparation/run
Week 12 Tue Next Generation sequencing approaches
Thurs Next Generation sequencing methods
Lab (Wed) Next Gen sequencing: data analysis
Week 13 Tue Next Generation sequencing data analysis
Thurs Next Generation sequencing applications |
Lab (Wed) Next Gen sequencing: applications

Week 14

Tue

Next Generation sequencing applications II

Thurs

Final Exam

Lab (Wed)

Open

Proteomic Methodologies in Biotechnology
BMS 312, Fall 2014
Syllabus

Lecture will be held on Tuesday and Thursday from 1:00pm - 2:20pm, TBD
(tentative Massy Conference Center)
Laboratory will be held on Friday from 1:00 — 4:00 pm, CRC 218

Course Director:

Qishan Lin, PhD

Department of Biomedical Sciences
School of Public Health

University at Albany, SUNY

Tel: (518)591-7214

glin@ albany.edu
Office hours: TBD

Teaching assistant: TBD

Course Description

The use of mass spectrometry in biomedical sciences has become increasingly
important as applications of the huge contribution from sequencing of human and
other genomes continue to impact research. The goal of this course is to provide
students with a solid theoretical background in advanced proteomics/mass
spectrometry technologies, hands on experience in the performance of many of
these techniques and an understanding of the instrumentation required to
perform them, and an appreciation for how these technological tools can be
applied to address research questions in the life sciences. The undergraduate
students learn about this cutting edge technology and gain new skills that we
believe will help them with their future scientific careers. The course will begin
with a brief review of basic analytical techniques such as SDS-PAGE,
chromatography and mass spectrometry. The main focus of the course will be
on such technologies as 2D gel electrophoresis, high pressure liquid
chromatography, mass spectrometry and the instrumentation required to apply
these technologies. Applications of the technologies will be highlighted, including
small molecular analysis, peptide and protein sequencing, protein expression
analysis, protein post-translational modifications, etc. The lecture topics will be
partnered with laboratory exercises that provide hands-on experience so that
students develop a more full understanding of these technologies. A focus will
be on the instrumentation required to perform the various technologies. While
instrument operation and data analysis will be highlighted, there will be significant
coverage of other key issues such as instrument design, maintenance, quality
control calibrations, and troubleshooting.

Prerequisites:
A CHM 120 General Chemistry |, or equivalent from another institution
A BIO 217 Cell Biology, or equivalent from another institution

Learning objectives

e You will be able to demonstrate additional depth of knowledge in systems
biology and proteomics.

e You will be able to critically evaluate the work of their peers in biomedical
sciences and will be able to identify the strengths and limitations of various
laboratory methodologies.

e You will be able to describe the role of proteomics in biomedical sciences

e You will learn to understand and communicate basic proteomics/mass
spec terminologies.

e You will learn about emerging proteomics technologies and how they can
be applied to diagnosis and prevention of human disease.

e You will learn where to locate and how to acquire accurate and practical
biological information that impacts human health issues.

e You will be able to explain the use of laboratory procedures for
understanding and diagnosing selected diseases and conditions.

e You will be able to understand the technologies used in the existing and
proposed programs in newborn, carrier, and cancer screening, and
discuss pros and cons of each program, including medical, economic,
ethical, legal, social and political factors.

Reading Materials

There is no assigned textbook for the course. Reading materials will be assigned by the course
instructor and posted on the course Blackboard site as appropriate. These readings will be
derived from the current scientific literature, and may change to reflect technological advances.
All readings will be available for student access prior to the appropriate lecture or laboratory
session.

Grading Scale:

The course will contain two lecture exams; the first is on the basic techniques of
proteomics and mass spectrometry and will serve as a mid-term exam; the
second will be comprehensive to help participants integrate the concepts being
presented in the course, and be considered a final exam. Performance
assessments of laboratory exercises will also be obtained in the form of 2-3 lab
reports.
For determining the final grade, 25% will consist of the mid-term exam grade,
50% will consist of the final exam grade, and 25% will consist of the average of
laboratory assessments.

A =93-100 A-=90-92

B+=87-89 B=83-88 B-=80-82
C+=77-79 C =73-78 C-=70-72
D+=67-69 D=63-68 D-=60-62

E =0-59

Note 1: The “earned” grad of “E” is treated mathematically as a “30”.

Note 2: Plagiarism without proper citation from any and all sources will result in
a grade of “E” for the course. Consult the Graduate Student Bulletins or the
course Instructors if you have any questions.

Attendance Policy

Attendance: Regular attendance is necessary for academic achievement in this

Safety:

course. The instructor should be notified promptly in case of
absence, with a valid reason provided. For absences related to
medical issues, please refer to the University’s Medical Excuse
Policy (www.albany.edu/health_center/medicalexcuse.shtml). If
absent from lecture, the student is responsible for all material
covered during that session. If absent from laboratory, the student
will be provided with an alternative exercise that will need to be
completed. More than three unexcused absences in lecture or
laboratory will result in a 5% reduction of the lecture or laboratory
component of the final course grade.

Students are required to adhere to the University’s laboratory safety
guidelines during laboratory sessions. These guidelines will be
reviewed during the first laboratory session.

Policy on Academic Integrity

Students are expected to adhere to university policies on academic
integrity (see
htto://www.albany.edu/undergraduate_bulletin/regulations.html). Any
form of academic dishonesty, including cheating or plagiarism, will

not be tolerated and will lead to disciplinary action as deemed
appropriate by the faculty and/or the University's judicial process.

From the University’s Standards of Academic Integrity Policy, Fall 2013:

“Every student has the responsibility to become familiar with the standards of academic integrity
at the University. Faculty members must specify in their syllabi information about academic
integrity, and may refer students to this policy for more information. Nonetheless, student claims
of ignorance, unintentional error, or personal or academic pressures cannot be excuses for
violation of academic integrity. Students are responsible for familiarizing themselves with the
standards and behaving accordingly, and UAlbany faculty are responsible for teaching, modeling
and upholding them. Anything less undermines the worth and value of our intellectual work, and
the reputation and credibility of the University at Albany degree.”

Class Schedule:

Week 1 Section 1 (Tue) Introduction
Section 2 (Thurs) | Review of basic analytical chemistry techniques
Section 3 (Fri) Lab safety
Week 2 Section 1 (Tue) Liquid chromatography
Section 2 (Thurs) | column-based chromatography
Section 3 (Fri) To be determined
Week 3 Section 1 (Tue) Electrophoresis 1

Section 2 (Thurs) | Electrophoresis 2

Section 3 (Fri) 1D SDS-PAGE 1

Week 4 Section 1 (Tue) 2D gel electrophoresis 1
Section 2 (Thurs) | 2D gel electrophoresis 2
Section 3 (Fri) 1D SDS-PAGE 2
Week 5 Section 1 (Tue) Methods of mass spectrometry 1
Section 2 (Thurs) | Methods of mass spectrometry 2
Section 3 (Fri) 2D gel electrophoresis 1
Week 6 Section 1 (Tue) Test1
Section 2 (Thurs) | Protein sequencing
Section 3 (Fri) 2D gel electrophoresis 2
Week 7 Section 1 (Tue) Recovery and fractionation of proteins using multi-

dimensional techniques

Section 2 (Thurs) | Interpretation of mass spectra 1

Section 3 (Fri) Mass spec 1

Week 8 Section 1 (Tue) Interpretation of mass spectra 2
Section 2 (Thurs) | ESI
Section 3 (Fri) 2D gel electrophoresis 2

Week 9 Section 1 (Tue) Introduction
Section 2 (Thurs) | Methods of mass spectrometry 3
Section 3 (Fri) Mass spec 2

Week 10 Section 1 (Tue) MALDI-TOF

Section 2 (Thurs) | Quantitative mass spectrometry

Section 3 (Fri) Mass spec 3

Week 11 Section 1 (Tue) Metabolite ID

Section 2 (Thurs)

Metabolomics

Section 3 (Fri)

Mass spec 4

Week 12

Section 1 (Tue)

Introduction to systems biology

Section 2 (Thurs)

Test 2

Section 3 (Fri)

Final test

Animal and Cell Culture Model Systems
BMS 314

Time/location: Spring 2015
T, Th 10:30-11:50 (lecture), TBD (tentative Massry Conference Center)
W 9:00-12:00 (laboratory), CRC 213 and 214

Course Instructor: Brian Parr, Ph.D.
Department of Biomedical Sciences
1 Discovery Drive, Room 342B
518-591-7213

bparr@albany.edu
Office hours TBD

Teaching assistant: TBD

Course Description

The goal of this course is to provide students with a solid background in advanced technologies
used to generate animal and cell culture models of human diseases. Laboratory exercises will be
utilized to further students’ understanding of the model systems and provide hands on
experience in the performance of widely used techniques. The course will begin with a brief
review of the most commonly used animal model systems. Techniques used to generate and
analyze these models will be discussed in detail. The use of cell culture and in vitro
differentiation systems as alternatives to animal models will be considered. Applications of the
technologies will include nucleic acid extraction from cells and tissues, histological examination
of tissues, laser capture microdissection, flow cytometry, and in vitro cell differentiation assays.

The lecture topics will be partnered with laboratory exercises that provide hands-on experience
so that students develop a more complete understanding of these technologies. A focus will be
on the instrumentation required to perform the various technologies. While instrument
operation and data analysis will be highlighted, there will be significant coverage of other key
issues such as experimental design and troubleshooting.

Prerequisite:

A BIO 212Y Introductory Genetics, or equivalent from another institution
A BIO 217 Cell Biology, or equivalent from another institution

Course Learning Objectives

1. Students will demonstrate an understanding of the uses of animal model systems in both
theory and performance.

2. Students will develop and demonstrate a thorough understanding of cell culture systems as
alternatives to animal models.

3. Students will demonstrate an understanding of in vitro differentiation systems as possible
alternatives to both cell culture and in vivo animal model systems.
4. Students will develop and demonstrate a thorough understanding of the analysis of
histological samples from animal models.

5. Students will develop and demonstrate a thorough understanding of laser capture
microdissection, the instrumentation required for its performance, and its use in isolating
cell populations from tissues of animal models.

6. Students will develop and demonstrate a thorough understanding of flow cytometry, the
instrumentation required for its performance, the analysis of flow cytometry data, and the
applications that are facilitated by this technology.

7. Students will demonstrate an understanding of the uses of in vitro differentiation systems.

8. Students will demonstrate an understanding and utilization of appropriate laboratory safety
procedures.

Class Policies:

Attendance: Regular attendance is necessary for academic achievement in this course. The
instructor should be notified promptly in case of absence, with a valid reason
provided. For absences related to medical issues, please refer to the University’s
Medical Excuse Policy (www.albany.edu/health_center/medicalexcuse.shtml). If
absent from lecture, the student is responsible for all material covered during that
session. If absent from laboratory, the student will be provided with an alternative
exercise that will need to be completed. More than three unexcused absences in
lecture or laboratory will result in a 5% reduction of the lecture or laboratory
component of the final course grade.

Safety: Students are required to adhere to the University’s laboratory safety guidelines
during laboratory sessions. These guidelines will be reviewed during the first
laboratory session.

Academic Integrity

Students are expected to adhere to university policies on academic integrity (see
http://www.albany.edu/undergraduate_bulletin/regulations.html). Any form of academic
dishonesty, including cheating or plagiarism, will not be tolerated and will lead to disciplinary
action as deemed appropriate by the faculty and/or the University's judicial process.

Course Grades

Two tests will be administered to assess the students’ comprehension of material covered in
lecture, a mid-term examination and a final examination. In addition, lecture homework will be
assigned and graded as described below. Performance assessments of each laboratory exercise
in the form of homework will also be assigned and graded.
The final grade weightings will consist of 10% from a mid-term examination, 15% from the final
examination, 50% from lecture homework assignments, and 25% from laboratory homework
assessments. Students will be assigned an alphabetical grade (A-F) for the course.

Homework Assignments

There will be 5 homework assignments during the semester (see course schedule for due dates).
Unless otherwise stated, the homework assignments will be posted one week prior to their due

date. The homework assignments will focus on exercises designed to further the understanding
of the most important concepts covered in the class. Homework assignments will be collected at
the beginning of the class when they are due. After the assignments are graded and returned to
students, answers will be posted on the course website.

Course Reading
Supplementary course material such as handouts and journal articles will be posted on the

course Blackboard site several days prior to the relevant course session. Journal article also may
be accessed via PubMed (http://www.ncbi.nim.nih.gov/pubmed/).

Students registered for the class can access the course material through the MyUalbany link to
Blackboard Learning System. Notes and readings will be posted as Adobe Acrobat (.pdf) or
Microsoft Word (.docx) files. Assignments will be distributed as Word files.

The primary course textbook will be R. lan Freshney “Culture of Animal Cells” (Wiley-Liss).
Following is a preliminary list of readings for the individual class sessions (also see course

schedule below). Readings will be updated as appropriate when more recent books/articles
become available.

Session 2-1 - Castrop, “Genetically modified mice—successes and failures of a widely
used technology”, Eur. J. Physiol. 459:557.2010.

Session 2-2 - Freshney, Chapter 23
Session 5-1 - Freshney, Chapter 11
Session 5-2 - Freshney, Chapter 20
Session 6-1 - Freshney, Chapter 12
Session 6-2 - Freshney, Chapter 14

Sessions 8-1 and 8-2 - Adams and van der Weyden, “Contemporary approaches for
modifying the mouse genome”, Physiol. Genomics34:225. 2008.

Sessions 10-1 and 10-2 - Freshney, Chapter 24
Session 11-2 - Yu and Thomson, “Pluripotent Stem Cell Lines”, Genes Dev. 22:1987,
2008.

Sessions 11-1, 12-1, and 12-2 - Murry and Keller, “Differentiation of Embryonic Stem

Cells to Clinically Relevant Populations: Lessons from Embryonic Development,
Cell 132:661.2008.

Course Schedule

The lecture portion of the class will meet twice a week for 80 minute sessions (approximately 26
lecture sessions total). Each topic will be covered during the course of 1-3 sessions. Laboratory
sessions will last for 3 hours, once a week. In the event that a student misses a laboratory
session due to illness or unexpected family emergency, they should contact the instructor to

make up the lab exercise using instructor generated data. The topics to be covered during the
course are as follows:
Session #

Class Topic (* = includes associated
laboratory exercise)

Material to be covered

Reading and homework
assignments

Week 1-1 Introduction to model systems Rationale for model systems
1-2 Widely used animal model systems Mouse, rat, pig, chick, frog, zebrafish, Drosophila
Lab 1 No laboratory meeting
Week 2-1 Detailed example of a model system Transgenic mice, strengths and weaknesses of Castrop article
different systems
2-2 Disease models Cancer models Chapter 23- Freshney
Lab 2 Molecular analysis of animal models
Week 3-1 Sample analysis |* RNA, DNA extraction Homework assignment 1 due
3-2 Sample analysis II* Histology- embedding, sectioning, staining tissues
Lab 3 Histological analysis of tissue from models
Week 4-1 Sample analysis III* Laser capture microdissection
4-2 Technologies for downstream analysis of End use of animal models Homework assignment 2 due
animal model systems
Lab 4 Laser capture microdissection
Week 5-1 Introduction to cell culture models Commonly used mammalian cell culture systems Chapter 11- Freshney
5-2 Cell culture methods | Culture and analysis of mammalian cell culture Chapter 20- Freshney
lines
Lab 5 Introduction to cell culture methods
Week 6-1 Cell culture methods II* Chapter 12- Freshney
6-2 Sample analysis |V* Flow cytometry Chapter 14- Freshney
Lab 6 Flow cytometry
Week 7-1 Mid-term examination
7-2 Introduction to stem cells Embryonic stem cells, adult stem cells, cancer stem
cells
Lab 7 Review of advanced cell culture methods
Week 8-1 Use of stem cells as model systems Gene targeting in stem cells Adams and van der Weyden
article
8-2 Stem cell culture* Culture of mammalian stem cells Adams and van der Weyden
article
Lab 8 ES cell culture
Week 9-1 In vivo vs. in vitro systems Relative merits of different types of model systems | Homework assignment 3 due

9-2

On line resources

Computer and internet resources for studying
model systems

Lab9 Computer exercises using on line
resources
Week 10-1 Organ culture systems Widely used organ culture systems such as kidneys | Chapter 24- Freshney
10-2 Methods of organ culture Chapter 24- Freshney
Lab 10 Establishment of a simple organ culture
system
Week 11-1 In vitro differentiation systems Homework assignment 4 due.
Murry and Keller article
11-2 Induced pluripotent stem cells iPS cells as a model system Yu and Thomson article
Lab 11 Culture of iPS cells
Week 12-1 In vitro differentiation of ES and iPS cells Techniques for generating diverse cell types from Murry and Keller article
ik ES/iPS cells
12-2 In vitro differentiation of ES and iPS cells Murry and Keller article
u*
Lab 12 In vitro differentiation assays
Week 13-1 Course review and final assignments due Homework assignment 5 due
13-2 Final Examination

Instrumentation in Biotechnology Research Internship, Molecular Core Lab
BMS 410, Spring Summer 2015
Course Syllabus:

Location and Meeting Times:
CRC 223, times TBD (100 hours total)

Course Director:

John Tine, Ph.D.

School of Public Health
University at Albany, SUNY
Cancer Research Center

1 Discovery Drive
Rensselaer, NY 12144

Tel: 518-591-7212

Office: CRC 342C, hours TBD
jtine@albany.edu

Course Description:

The goal of this internship course is to provide students with research experiences in the
UAlbany Cancer Research Center’s Molecular Biology laboratory where they will gain practical,
hands-on experience with the use of instrumentation in molecular biology in a core laboratory
environment. Students will perform molecular biological experiments required for projects in
the core laboratory as determined by the laboratory director and supervising laboratory staff.
This experience will build on prior course work that has provided students with an
understanding of the theory, operation, and application of instrumentation in molecular biology.

Prerequisite:
BMS 310 Molecular and Genomic Approaches in Biotechnology |
Student Objectives:

e Students will demonstrate laboratory skills in molecular biology by performing
experiments in the molecular biology core laboratory. Attendance for ~7 hours/week
will be required.

e Students will demonstrate an understanding of the theory, operation, and application of
instrumentation in molecular biology.

e Students will demonstrate the ability to keep accurate written records of their
laboratory activities.

e Students will demonstrate appropriate conduct in the laboratory environment.

e Students will demonstrate an understanding and utilization of appropriate laboratory
safety procedures.
Grading:

Assessments of the student’s performance in the laboratory will occur at midterm and at the
end of the semester. The evaluation will use a skills rubric that assesses the student’s
performance with regard to lab protocols, technical skill, behavior, and communication. The
evaluation will be performed by the laboratory director with input from lab staff as appropriate.
The final grade will be based on the results of these assessments, with the midterm assessment
contributing 40% and the final assessment contributing 60% toward the final grade.

The grading scale for the course is follows:

A= 93-100 A- = 90-92
B+ = 87-89 B = 83-88
C+ = 77-79 C= 73-78
D+ = 67-69 D = 63-68 D- = 60-62
E=0-59

Class Policies:

Attendance: Students will fulfill a time requirement of 100 hours during the course of the
semester, with a schedule mutually agreed on by the student and Course Director.
Failure to complete the time requirement will result in a grade of E.

Safety: Students are required to adhere to the University’s laboratory safety guidelines
while in the laboratory. These guidelines will be reviewed at the beginning of the
internship.

Academic Integrity:

Students are expected to adhere to university policies on academic integrity (see
http://www.albany.edu/undergraduate_bulletin/regulations.html). Any form of
academic dishonesty will not be tolerated and will lead to disciplinary action as
deemed appropriate by the faculty and/or the University's judicial process.

From the University’s Standards of Academic Integrity Policy, Fall 2013:

“Every student has the responsibility to become familiar with the standards of academic integrity
at the University. Faculty members must specify in their syllabi information about academic
integrity, and may refer students to this policy for more information. Nonetheless, student claims
of ignorance, unintentional error, or personal or academic pressures cannot be excuses for
violation of academic integrity. Students are responsible for familiarizing themselves with the
standards and behaving accordingly, and UAlbany faculty are responsible for teaching, modeling
and upholding them. Anything less undermines the worth and value of our intellectual work, and
the reputation and credibility of the University at Albany degree.”

Course Schedule:

Week 1: Students will meet with laboratory director/supervisory staff to discuss
activities, begin laboratory safety training, begin laboratory work
Weeks 2-14: Weekly attendance, performance of laboratory work, documentation of hours
and work performed

Evaluation: Performed by laboratory director with appropriate input from supervisory
laboratory staff at midterm and the end of the semester

Total hours required: 100
Instrumentation in Biotechnology Research Internship, Proteomics Core Lab
BMS 411, Spring Summer 2015
Course Syllabus:

Location and Meeting Times:
CRC 330, times TBD (100 hours total)

Course Director:

Qishan Lin, PhD

Department of Biomedical Sciences
School of Public Health

University at Albany, SUNY

Cancer Research Center

1 Discovery Drive

Rensselaer, NY 12144

Tel: (518)591-7214

Office: CRC 342H, hours TBD
glin@albany.edu

Course Description:

The goal of this internship course is to provide students with research experiences in the
UAlbany Cancer Research Center’s Proteomics laboratory where they will gain practical, hands-
on experience with the use of instrumentation in proteomics in a core laboratory environment.
Students will perform genomics experiments required for projects in the core laboratory as
determined by the laboratory director and supervising laboratory staff. This experience will
build on prior course work that has provided students with an understanding of the theory,
operation, and application of instrumentation in proteomics.

Prerequisite:

BMS 312 Proteomic Methodologies in Biotechnology

Student Objectives:

e Students will demonstrate laboratory skills in proteomics by performing experiments in
the proteomics core laboratory. Attendance for ~7 hours/week will be required.

e Students will demonstrate an understanding of the theory, operation, and application of
instrumentation in proteomics.

e Students will demonstrate the ability to keep accurate written records of their
laboratory activities.

e Students will demonstrate appropriate conduct in the laboratory environment.

e Students will demonstrate an understanding and utilization of appropriate laboratory
safety procedures.
Grading:

Assessments of the student’s performance in the laboratory will occur at midterm and at the
end of the semester. The evaluation will use a skills rubric that assesses the student’s
performance with regard to lab protocols, technical skill, behavior, and communication. The
evaluation will be performed by the laboratory director with input from lab staff as appropriate.
The final grade will be based on the results of these assessments, with the midterm assessment
contributing 40% and the final assessment contributing 60% toward the final grade.

The grading scale for the course is follows:

A= 93-100 A- = 90-92
B+ = 87-89 B = 83-88
C+ = 77-79 C= 73-78
D+ = 67-69 D = 63-68 D- = 60-62
E=0-59

Class Policies:

Attendance: Students will fulfill a time requirement of 100 hours during the course of the
semester, with a schedule mutually agreed on by the student and Course Director.
Failure to complete the time requirement will result in a grade of E.

Safety: Students are required to adhere to the University’s laboratory safety guidelines
while in the laboratory. These guidelines will be reviewed at the beginning of the
internship.

Academic Integrity:

Students are expected to adhere to university policies on academic integrity (see
http://www.albany.edu/undergraduate_bulletin/regulations.html). Any form of
academic dishonesty will not be tolerated and will lead to disciplinary action as
deemed appropriate by the faculty and/or the University's judicial process.

From the University’s Standards of Academic Integrity Policy, Fall 2013:

“Every student has the responsibility to become familiar with the standards of academic integrity
at the University. Faculty members must specify in their syllabi information about academic
integrity, and may refer students to this policy for more information. Nonetheless, student claims
of ignorance, unintentional error, or personal or academic pressures cannot be excuses for
violation of academic integrity. Students are responsible for familiarizing themselves with the
standards and behaving accordingly, and UAlbany faculty are responsible for teaching, modeling
and upholding them. Anything less undermines the worth and value of our intellectual work, and
the reputation and credibility of the University at Albany degree.”

Course Schedule:

Week 1: Students will meet with laboratory director/supervisory staff to discuss
activities, begin laboratory safety training, begin laboratory work
Weeks 2-14: Weekly attendance, performance of laboratory work, documentation of hours
and work performed

Evaluation: Performed by laboratory director with appropriate input from supervisory
laboratory staff at midterm and the end of the semester

Total hours required: 100
Instrumentation in Biotechnology Research Internship, Genomics Core Lab
BMS 412, Spring Summer 2015
Course Syllabus:

Location and Meeting Times:
CRC 328, times TBD (100 hours total)

Course Director:

Sridar V. Chittur PhD

Department of Biomedical Sciences
School of Public Health

Director, Microarray & HT Sequencing Core
University at Albany, SUNY

Center for Functional Genomics
Cancer Research Center

One Discovery Dr

Rensselaer, NY 12144

Office: CRC 342G, hours TBD
Tel:518-591-7215
schittur@albany.edu

Course Description:

The goal of this internship course is to provide students with research experiences in the
UAlbany Cancer Research Center’s Microarray laboratory where they will gain practical, hands-
on experience with the use of instrumentation in genomics in a core laboratory environment.
Students will perform genomics experiments required for projects in the core laboratory as
determined by the laboratory director and supervising laboratory staff. This experience will
build on prior course work that has provided students with an understanding of the theory,
operation, and application of instrumentation in genomics.

Prerequisite:
BMS 311 Molecular and Genomic Approaches in Biotechnology II
Student Objectives:

e Students will demonstrate laboratory skills in genomics by performing experiments in
the microarray core laboratory. Attendance for ~7 hours/week will be required.

e Students will demonstrate an understanding of the theory, operation, and application of
instrumentation in genomics.

e Students will demonstrate the ability to keep accurate written records of their
laboratory activities.

e Students will demonstrate appropriate conduct in the laboratory environment.

e Students will demonstrate an understanding and utilization of appropriate laboratory
safety procedures.
Grading:

Assessments of the student’s performance in the laboratory will occur at midterm and at the
end of the semester. The evaluation will use a skills rubric that assesses the student’s
performance with regard to lab protocols, technical skill, behavior, and communication. The
evaluation will be performed by the laboratory director with input from lab staff as appropriate.
The final grade will be based on the results of these assessments, with the midterm assessment
contributing 40% and the final assessment contributing 60% toward the final grade.

The grading scale for the course is follows:

A= 93-100 A- = 90-92
B+ = 87-89 B = 83-88
C+ = 77-79 C= 73-78
D+ = 67-69 D = 63-68 D- = 60-62
E=0-59

Class Policies:

Attendance: Students will fulfill a time requirement of 100 hours during the course of the
semester, with a schedule mutually agreed on by the student and Course Director.
Failure to complete the time requirement will result in a grade of E.

Safety: Students are required to adhere to the University’s laboratory safety guidelines
while in the laboratory. These guidelines will be reviewed at the beginning of the
internship.

Academic Integrity:

Students are expected to adhere to university policies on academic integrity (see
http://www.albany.edu/undergraduate_bulletin/regulations.html). Any form of
academic dishonesty will not be tolerated and will lead to disciplinary action as
deemed appropriate by the faculty and/or the University's judicial process.

From the University’s Standards of Academic Integrity Policy, Fall 2013:

“Every student has the responsibility to become familiar with the standards of academic integrity
at the University. Faculty members must specify in their syllabi information about academic
integrity, and may refer students to this policy for more information. Nonetheless, student claims
of ignorance, unintentional error, or personal or academic pressures cannot be excuses for
violation of academic integrity. Students are responsible for familiarizing themselves with the
standards and behaving accordingly, and UAlbany faculty are responsible for teaching, modeling
and upholding them. Anything less undermines the worth and value of our intellectual work, and
the reputation and credibility of the University at Albany degree.”

Course Schedule:

Week 1: Students will meet with laboratory director/supervisory staff to discuss
activities, begin laboratory safety training, begin laboratory work
Weeks 2-14: | Weekly attendance, performance of laboratory work, documentation of hours
and work performed

Evaluation: Performed by laboratory director with appropriate input from supervisory
laboratory staff at midterm and the end of the semester

Total hours required: 100
Instrumentation in Biotechnology Research Internship, Cell Analysis Core Lab
BMS 414, Spring Summer 2015
Course Syllabus:

Location and Meeting Times:
CRC 332, times TBD (100 hours total)

Course Director:

Brian Parr, Ph.D.

Department of Biomedical Sciences
School of Public Health

University at Albany, SUNY

Cancer Research Center

1 Discovery Drive

Rensselaer, NY 12144

Office: CRC 342B, hour TBD
518-591-7213

bparr@albany.edu

Course Description:

The goal of this internship course is to provide students with research experiences in the
UAlbany Cancer Research Center’s Mouse Transgenics laboratory where they will gain practical,
hands-on experience with the use of instrumentation in cell analysis in a core laboratory
environment. Students will perform cell analysis experiments required for projects in the core
laboratory as determined by the laboratory director and supervising laboratory staff. This
experience will build on prior course work that has provided students with an understanding of
the theory, operation, and application of instrumentation in cell analysis.

Prerequisite:
BMS 314 Animal and Cell Culture Model Systems
Student Objectives:

e Students will demonstrate laboratory skills in cell analysis by performing experiments in
the mouse transgenics core laboratory. Attendance for ~7 hours/week will be required.

e Students will demonstrate an understanding of the theory, operation, and application of
instrumentation in cell analysis.

e Students will demonstrate the ability to keep accurate written records of their
laboratory activities.

e Students will demonstrate appropriate conduct in the laboratory environment.

e Students will demonstrate an understanding and utilization of appropriate laboratory
safety procedures.
Grading:

Assessments of the student’s performance in the laboratory will occur at midterm and at the
end of the semester. The evaluation will use a skills rubric that assesses the student’s
performance with regard to lab protocols, technical skill, behavior, and communication. The
evaluation will be performed by the laboratory director with input from lab staff as appropriate.
The final grade will be based on the results of these assessments, with the midterm assessment
contributing 40% and the final assessment contributing 60% toward the final grade.

The grading scale for the course is follows:

A= 93-100 A- = 90-92
B+ = 87-89 B = 83-88
C+ = 77-79 C= 73-78
D+ = 67-69 D = 63-68 D- = 60-62
E=0-59

Class Policies:

Attendance: Students will fulfill a time requirement of 100 hours during the course of the
semester, with a schedule mutually agreed on by the student and Course Director.
Failure to complete the time requirement will result in a grade of E.

Safety: Students are required to adhere to the University’s laboratory safety guidelines
while in the laboratory. These guidelines will be reviewed at the beginning of the
internship.

Academic Integrity:

Students are expected to adhere to university policies on academic integrity (see
http://www.albany.edu/undergraduate_bulletin/regulations.html). Any form of
academic dishonesty will not be tolerated and will lead to disciplinary action as
deemed appropriate by the faculty and/or the University's judicial process.

From the University’s Standards of Academic Integrity Policy, Fall 2013:

“Every student has the responsibility to become familiar with the standards of academic integrity
at the University. Faculty members must specify in their syllabi information about academic
integrity, and may refer students to this policy for more information. Nonetheless, student claims
of ignorance, unintentional error, or personal or academic pressures cannot be excuses for
violation of academic integrity. Students are responsible for familiarizing themselves with the
standards and behaving accordingly, and UAlbany faculty are responsible for teaching, modeling
and upholding them. Anything less undermines the worth and value of our intellectual work, and
the reputation and credibility of the University at Albany degree.”

Course Schedule:

Week 1: Students will meet with laboratory director/supervisory staff to discuss
activities, begin laboratory safety training, begin laboratory work
Weeks 2-14: Weekly attendance, performance of laboratory work, documentation of hours
and work performed

Evaluation: Performed by laboratory director with appropriate input from supervisory
laboratory staff at midterm and the end of the semester

Total hours required: 100
Instrumentation in Biotechnology Research Internship, Academic Lab
BMS 415, Spring Summer 2015
Course Syllabus:

Location and Meeting Times:
CRC various, times TBD (100 hours total)

Course Director:

Martin Tenniswood, PhD
Department of Biomedical Sciences
School of Public Health

University at Albany, SUNY

Cancer Research Center

1 Discovery Drive

Rensselaer, NY 12144

Tel: (518)591-7200

Office: CRC 304C, hours TBD
mtenniswood@albany.edu

Course Description:

The goal of this internship course is to provide students with research experiences in an
academic laboratory of the UAlbany Cancer Research Center where they will gain practical,
hands-on experience with the use of instrumentation in molecular biology, genomics,
proteomics, or cell analysis in an academic laboratory environment. Students will perform
experiments required for projects in the academic laboratory as determined by the laboratory
principle investigator and supervising laboratory staff. This experience will build on prior course
work that has provided students with an understanding of the theory, operation, and
application of instrumentation in molecular biology, genomics, proteomics, and cell analysis.

Students can choose from CRC academic laboratories under the direction of the following
principle investigators, with the agreement of the principle investigator required prior to
registration:

Martin Tenniswood, Ph.D.
JoEllen Welsh, Ph.D.
Douglas Conklin, Ph.D
Ramune Reliene, Ph.D.
Jason Herschkowitz, Ph.D.

Prerequisites:
BMS 310 Molecular and Genomic Approaches in Biotechnology |

BMS 312 Proteomic Methodologies in Biotechnology
BMS 314 Animal and Cell Culture Model Systems
Student Objectives:

e Students will demonstrate laboratory skills in molecular biology, genomics, proteomics,
or cell analysis by performing experiments in the academic laboratory. Attendance for
~7 hours/week will be required.

e Students will demonstrate an understanding of the theory, operation, and application of
instrumentation in molecular biology, genomics, proteomics, or cell analysis.

e Students will demonstrate the ability to keep accurate written records of their
laboratory activities.

e Students will demonstrate appropriate conduct in the laboratory environment.

e Students will demonstrate an understanding and utilization of appropriate laboratory
safety procedures.

Grading:

Assessments of the student’s performance in the laboratory will occur at midterm and at the
end of the semester. The evaluation will use a skills rubric that assesses the student’s
performance with regard to lab protocols, technical skill, behavior, and communication. The
evaluation will be performed by the laboratory director with input from lab staff as appropriate.
The final grade will be based on the results of these assessments, with the midterm assessment
contributing 40% and the final assessment contributing 60% toward the final grade.

The grading scale for the course is follows:

A= 93-100 A- = 90-92

B+ = 87-89 B = 83-88 B- = 80-82
C+ = 77-79 C=73-78
D+ = 67-69 D = 63-68
E=0-59

Class Policies:

Attendance: Students will fulfill a time requirement of 100 hours during the course of the
semester, with a schedule mutually agreed on by the student and Course Director.
Failure to complete the time requirement will result in a grade of E.

Safety: Students are required to adhere to the University’s laboratory safety guidelines
while in the laboratory. These guidelines will be reviewed at the beginning of the
internship.

Academic Integrity:

Students are expected to adhere to university policies on academic integrity (see
http://www.albany.edu/undergraduate_bulletin/regulations.html). Any form of
academic dishonesty will not be tolerated and will lead to disciplinary action as
deemed appropriate by the faculty and/or the University's judicial process.

From the University’s Standards of Academic Integrity Policy, Fall 2013:

“Every student has the responsibility to become familiar with the standards of academic integrity
at the University. Faculty members must specify in their syllabi information about academic
integrity, and may refer students to this policy for more information. Nonetheless, student claims
of ignorance, unintentional error, or personal or academic pressures cannot be excuses for
violation of academic integrity. Students are responsible for familiarizing themselves with the
standards and behaving accordingly, and UAlbany faculty are responsible for teaching, modeling
and upholding them. Anything less undermines the worth and value of our intellectual work, and
the reputation and credibility of the University at Albany degree.”

Course Schedule:

Week 1: Students will meet with laboratory director/supervisory staff to discuss
activities, begin laboratory safety training, begin laboratory work

Weeks 2-14: Weekly attendance, performance of laboratory work, documentation of hours
and work performed

Evaluation: Performed by laboratory director with appropriate input from supervisory
laboratory staff at midterm and the end of the semester

Total hours required: 100
Bio-Instrumentation Cooperative Training Internship
BMS 420, Fall 2015
Course Syllabus:

Location and Meeting Times:
CRC or various local laboratories, times TBD (100 hours total)

Course Director:

Martin Tenniswood, PhD
Department of Biomedical Sciences
School of Public Health

University at Albany, SUNY

Cancer Research Center

1 Discovery Drive

Rensselaer, NY 12144

Tel: (518)591-7200

Office: CRC 304C, hours TBD
mtenniswood@albany.edu

Course Description:

The goal of this internship course is to provide students with real-world experience in the use of
biotechnological instrumentation to address broader research questions, as well as an
understanding of the expectations that come with a professional career in laboratory research.
Students will perform cooperative training with local biotechnology companies or larger
academic laboratories. This research experience will build on prior course work and internships
that have provided students with both practical experience with and an understanding of the
theory, operation, and application of instrumentation in molecular biology, genomics,
proteomics, and cell analysis research.

Internships will be arranged in consultation with the Course Director. Placements may include
academic laboratories within UAlbany or at other area institutions, or local biotechnology
companies. A selection of the local companies who have agreed to participate in this course
includes:

Bioharvest, Ltd.

Regeneron Pharmaceuticals
Intidyn

Ultradian Diagnostics

Next Advance

Prerequisites:
Completion of any two of the following:

BMS 410 Instrumentation in Biotechnology Internship, Molecular Biology Core Lab
BMS 411 Instrumentation in Biotechnology Internship, Proteomics Core Lab
BMS 412 Instrumentation in Biotechnology Internship, Genomics Core Lab
BMS 414 Instrumentation in Biotechnology Internship, Cell Analysis Core Lab
BMS 415 Instrumentation in Biotechnology Internship, Academic Lab

Student Objectives:

e Students will demonstrate professional laboratory skills by working in the biotechnology
or academic laboratory. Attendance for ~7 hours/week will be required.

e Students will demonstrate appropriate conduct in the laboratory environment and
follow laboratory-specific standards.

e Students will demonstrate an understanding and utilization of appropriate laboratory
safety procedures.

Grading:

Assessments of the student’s performance in the laboratory will occur at midterm and at the
end of the semester. The evaluation will use a skills rubric that assesses the student’s
performance with regard to lab protocols, technical skill, behavior, and communication. The
evaluation will be performed by the laboratory director with input from lab staff as appropriate.
The final grade will be based on the results of these assessments, with the midterm assessment
contributing 40% and the final assessment contributing 60% toward the final grade.

The grading scale for the course is follows:

A= 93-100 A- = 90-92
B+ = 87-89 B = 83-88
C+ = 77-79 C=73-78
D+ = 67-69 D = 63-68 D- = 60-62
E=0-59

Class Policies:

Attendance: Students will fulfill a time requirement of 100 hours during the course of the
semester, with a schedule mutually agreed on by the student and supervisor at
the host laboratory. Failure to complete the time requirement will result in a

grade of E.

Safety: Students are required to adhere to the host laboratory’s safety guidelines and
other policies. These guidelines/policies will be reviewed at the beginning of the
internship.

Academic Integrity:

Students are expected to adhere to university policies on academic integrity (see
http://www.albany.edu/undergraduate_bulletin/regulations.html). Any form of
academic dishonesty will not be tolerated and will lead to disciplinary action as
deemed appropriate by the faculty and/or the University's judicial process.

From the University’s Standards of Academic Integrity Policy, Fall 2013:

“Every student has the responsibility to become familiar with the standards of academic integrity
at the University. Faculty members must specify in their syllabi information about academic
integrity, and may refer students to this policy for more information. Nonetheless, student claims
of ignorance, unintentional error, or personal or academic pressures cannot be excuses for
violation of academic integrity. Students are responsible for familiarizing themselves with the
standards and behaving accordingly, and UAlbany faculty are responsible for teaching, modeling
and upholding them. Anything less undermines the worth and value of our intellectual work, and
the reputation and credibility of the University at Albany degree.”

Course Schedule:

Week 1: Students will meet with laboratory director/supervisory staff to discuss
activities, begin laboratory safety training, begin laboratory work

Weeks 2-14: Weekly attendance, performance of laboratory work, documentation of hours
and work performed

Evaluation: Performed by laboratory director with appropriate input from supervisory
laboratory staff at midterm and the end of the semester

Total hours required: 100
University at Albany
Program Revision — Interdisciplinary Studies

Appendix 2

Program Schedule and Curriculum
SUNY Undergraduate Sample Program Schedule

‘Campus Name University at Albany, State University of New York

Program/Track Title and Award [BS in Interdisciplinary Studies, with a faculty-initiated concentration in Bio-Instrumentation
Semener Gare Trimester other

Calendar Type Ix l ]

SUNY Transfer Path Name (if one exists) [ ] - Use Dropdown Arrow.

Use the table to show how a typical student may progress through the program. Check all columns that apply to a course or enter credits where applicable.

KEY Course Type: Required (R), Restricted Elective (RE), Free Elective (FE). Course Credits: Number of Credits for individual course (Enter number.) GER Area: SUNY General Education Requirement Area (Enter Area Abbreviation from the drop-down menu.) GER Credits: (Enter number of course
credits.) LAS: Liberal Arts & Sciences Credits (Enter X if course isan LAS course.) Major: Major requirement (Enter X.) TPath: SUNY Transfer Path Major & Cognate Courses (Enter X.) Elective/Other: Electives or courses other than specified categories (Enter X.) Upper Div: Courses intended
primarily for juniors and seniors outside of the major (Enter X.) Upper Div Major: Courses intended primarily for juniors and seniors within the major (Enter X.) New: new course (Enter X.) Co/Prerequiste(s) List co/prerequisite(s) for the noted courses. SUNY GER Area Abbreviations (the first five
listed in order of their frequency of being required by SUNY campuses): Basic Communication (BC), Math (M), Natural Sciences (NS), Social Science (SS), Humanities (H), American History (AH), The Arts (AR), Other World Civilizations (OW), Western Civilization (WC), Foreign Language (FL).
‘The table will automatically update the number of credits, courses and categories in the program totals table at the bottom of the chart.

Label each term in sequence, consistent with the insttution’s academic calendar (e.g. Fall 1, Spring 1, Fall.

Tal

[course Number & Title (8 Type) Number of Credits] GER Area GE Credits Las Major Elective/Other Upper Div__|_Upper Div Major Path New Course Co/Prerequisite
[ABIO 120 General Biology 1-R 3 NS 3 x

[ACHNN 120 - General Chemistry 1-R 3 NS 3 x x

[ACHN 124 - General Chemistry 1 lab-R 1 x x

[AMAT 108 - Elementary Statistics -R 3 Mi 3 x x

Humanities Gen Ed - RE 3 H 3 x

[Social Science Gen Ed RE, 3 ss 3 x

[Term Totals 16 5 5 16 0 ba
Spring T

[Course Number & Title (8 Type) Number of Credits| GER Area GE Credits Las Major Elective/Other Upper Div__|_Upper Div Major Path New Course Co/Prerequisite
[ABIO 123 - General Biology 11-8 3 NS 3 x x BIO 120

[ACHN 121 - General Chemistry 11 - 3 NS 3 x x [ACHM 120

[ACHM 125 - General Chemistry 11 fab-R 1 x x

[AMAT 112 Calculus 1-R 4 Mi 4 x x

[UNI 110 - Writing and Critical Inguiry-R 3 BC 3 x

Herm Totals i 4 B ia Ey oH

Tal

|course Number & Title (& Type) Number of Credits| GER Area GE Credits Las Major Elective/Other Upper div __| Upper Div Major ‘Path New Course Co/Prerequisite
[APHY 140 -Physies 2 3 NS 3 x x

[APHY 145 - Physics 1 Lab 1 x x

[ACHM 220 - Organic Chemistry -R 3 x x [ACH 120

[ACH 222 - Organic Chemistry Lab -R 1 x x [ACHM 220

[ABIO 203 - Intro to Biological Investigation 1 R 1 x x iO 124/cHM 121/CHM 125
Foreign Language Gen Ed - RE 4 FL 4 x

International Perspectives Gen Ed - RE 3 ‘ow 3 x

[Term Totals 16 3 10 36 3 ba
Spring?

[course Number & Title (8 Type) Number of Credits| GER Area GE Credits Las Major Elective/Other Upper Div__|_Upper Div Major Path New Course Co/Prerequisite
[ABI 2022. intro to Biological Investigations 11 -R 1 x x iG 424/cHNM a2i/CHM 125
[ABIO 212 -Genetics-R 4 x x ABi0 421

[ABIO 217 - Cell Biology -R 3 x x ABio 121

US Gen Ed- RE 3 aA 3 x

larts Gen €d- RE 3 AR 3 x

[Term Totals i z 6 Ea 3 ca

Taig

|course Number & Title (& Type) Number of Credits | GER Area GE Credits las Major Elective/Other Upper Div__| Upper Div Major path New Course Co/Prerequisite
SPH 201- Introduction to Public Health - 3 x x
[HBMS 310 Molecular & Genomic Apps in Biotech 1- 4 x x x x [ABIO 212, ABIO 217
HEM 312 - Proteomic Methodologies in Biotech -R 4 x x x x [ACHM 120, ABIO 217
[challenges in the 21st Century Gen Ed- RE 3 x
[Upper level Elective - FE 2 x x
Herm Totals 16 @ a z 10 a z CH)
Springs
|course Number & Title (& Type) Number of Credits | GER Area GE Credits las Major Elective/Other Upper Div__| Upper Div Major path New Course Co/Prerequisite
HSPH 231 - Concepts in Epidemiology -R 3 x x [AMAT 108
[Has 221 - Molecular & Genomic Apps in Biotech 11-8 4 x x x x BMS 310
HBMS 314 - Animal and Cell Culture Model Systems-R 4 x x x x [ABIO 212, ABIO 217
HBMS - Biotechnology Research Internship -R 3 x x x x BMS 300 level
(Choose between HBMS 410,411,412,414,415)
Herm Totals i a i Ey Ey 3 Cc)
alt
|course Number & Title (& Type) Number of Credits | GER Area GE Credits las Major Elective/Other Upper Div__|_Upper Div Major Path New Course Co/Prerequisite
[HBMS 505 - Biological Basis of Public Health 3 x x x [ABI 120
HBMS - Biotechnology Research Internship -R 3 x x x x BMS 300 level
(Choose between HBMS 410,411,412,414,415)
HSPH 332 - Intro to Biostatistics -R 3 x x x AMAT 108
Elective -FE 3 x
[Upper level elective - FE 3 x x
Herm Totals cy 3 G uy 3 z cH
Spring
|course Number & Title (& Type) Number of Credits | GER Area GE Credits las Major Elective/Other Upper Div__|_Upper Div Major path New Course CofPrerequisite
HBMS - Bio-Instrumentation Co-op Training Intern - R 3 x x x
Elective -FE 3 x x [Two HEMS 400 levels
[Upper level elective - FE 3 x x
[Upper level elective - FE 3 x x
[Upper level elective - FE 3 x x
[Term Totals 5 3 Ft 2D 3 i oD
Program Total Summary Total Ged SUNY GERAress —] SUNY GERCredit | Uberal Ants Sciences | MajorCredi ] Elertveand Other ] Upper Dvsion Gets | Upper Dwsion Major ] Total Path Courses | Naw Courses
Credits Credits Credits
120 A 44 69 A 20 a5 31 z

GER Area Summary Basie Communication (BC) T “The Arts (AR) T

Mathematics (M) 2 ‘American History (AH) a

Natural Sciences (NS) 5 Western Civilization (WC)

Social Sciences (SS) a Other World Civilizations (OW) a

Humanities (H) 1 Foreign Language (FL) 1

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